Hodgkin’s Hasenclever

By clicking on the “Submit” button below, you acknowledge that you have read, understand, and agree to be bound by the terms of the QxMD Online Calculator End User Agreement.

Use this calculator to determine prognosis in advanced Hodgkin’s disease using the Hasenclever Hodgkin’s Prognosis Score (IPS).

Age ≥ 45
Gender
Albumin < 40 g/L
Hemoglobin < 105 g/L
Stage
Leukocytosis ≥ 15,000 per mm3
Lymphopenia

_

About this calculator

The Hasenclever International Prognostic Score (IPS) was designed to predict five-year freedom from progression of disease. With each additional adverse prognostic factor, the predicted rate is reduced by approximately 8%. The score was developed and validated based on a set of patients being treated in the 1980s with regimens including ABVD, MOPP and ABVD, and similar hybrid regimens. Treatment variations did not appear to affect the validity of the prognostic score.

Citation

The IPS was developed by Hasenclever D and Diehlt. A prognostic score for advanced Hodgkins’s disease. NEJM 339:1506-14. (1998)

_

Contributor

QxMD Hematology contributing author: Dr. Matthew Cheung, MD, SM, FRCP(C)