Bode Index

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Use this calculator to calculate prognosis in COPD (Chronic Obstructive Pulmonary Disease) using the BODE Index.

FEV1 (% predicted)
6-minute walk distance (m)
Modified MRC Dyspnea Scale
0: Dyspneic on strenuous exercise
1: Dyspneic on walking a slight hill
2: Dyspneic on walking level ground; must stop occasionally due to breathlessness
3: Must stop for breathlessness after walking 100 yards or after a few minutes
4: Cannot leave house; breathless on dressing/undressing
Body Mass Index (kg/m2)

About this calculator

This formula is taken from Celli et al (2004), based on the evaluation of 207 patients with COPD and the subsequent prospective validation on a similar cohort of 625 patients. Patients were recruited in the United States, Venezuela, and Spain and all were judged to have stable COPD.

61% of deaths were secondary to respiratory insufficiency. Multiple variables were assessed and each was evaluated as a possible independent predictor of mortality. FEV1, body-mass index, 6-minute walk distance, and the modified MRC dyspnea scale were found to be the best predictors of death among these variables. The BODE Index predicts all-cause mortality and respiratory-related mortality with better accuracy than the FEV1 alone.

The hazard ratio for all-cause mortality is 1.34 for every one-point increase in the BODE score. The hazard ratio for respiratory-related mortality is 1.62 for every one-point increase in the BODE score.

Citation

Celli BR et al. The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease. NEJM 2004;350:1005.  View full text

Suggested Reading:

Celli BR et al. Predictors of Survival in COPD: More than Just the FEV1. Respir Med 2008;102(Suppl 1):S27.

Contributor

QxMD Respirology contributing author: Dr. Christopher Ryerson, MD, FRCP(C)