We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
Review
Imaging osteomyelitis and the diabetic foot.
Quarterly Journal of Nuclear Medicine 1999 March
BACKGROUND: The clinical diagnosis of osteomyelitis and the diabetic foot is in most of the patients not possible without imaging the bone. The clinical problem is to diagnose infection as early, as reliable and as cheap as possible to prevent the possible longstanding and life-threatening complications.
METHODS: For imaging a lot of different radiological and nuclear medicine methods are available. This article focuses on the possible results of conventional plain radiography and tomography, computed tomography and magnetic resonance imaging as radiological methods and on bone scan, autologous white blood cell scintigraphy with 111In-oxin or 99mTc-HMPAO, antigranulocyte antibodies, 99mTc-/111In-human immunoglobulin, 67Ga-citrate and 99mTc-nanocolloids.
RESULTS: Different methods offer different answers. Radiological methods give detailed pathological answers, nuclear medicine methods answer questions of specificity such as leukocytic infiltration.
CONCLUSIONS: If osteomyelitis is suspected, plain radiography should be the first, three phase bone scintigraphy the second and infection specific radiopharmaceuticals the third step of examination. Only in negative images with high clinical suspicion CT or MRI should be the final imaging procedure. In the diabetic foot imaging cascade should also start with plain radiography, followed by three phase bone scintigraphy or MRI. If clinically neuropathy is present specific nuclear medicine imaging should be performed.
METHODS: For imaging a lot of different radiological and nuclear medicine methods are available. This article focuses on the possible results of conventional plain radiography and tomography, computed tomography and magnetic resonance imaging as radiological methods and on bone scan, autologous white blood cell scintigraphy with 111In-oxin or 99mTc-HMPAO, antigranulocyte antibodies, 99mTc-/111In-human immunoglobulin, 67Ga-citrate and 99mTc-nanocolloids.
RESULTS: Different methods offer different answers. Radiological methods give detailed pathological answers, nuclear medicine methods answer questions of specificity such as leukocytic infiltration.
CONCLUSIONS: If osteomyelitis is suspected, plain radiography should be the first, three phase bone scintigraphy the second and infection specific radiopharmaceuticals the third step of examination. Only in negative images with high clinical suspicion CT or MRI should be the final imaging procedure. In the diabetic foot imaging cascade should also start with plain radiography, followed by three phase bone scintigraphy or MRI. If clinically neuropathy is present specific nuclear medicine imaging should be performed.
Full text links
Related Resources
Trending Papers
Systemic lupus erythematosus.Lancet 2024 April 18
Should renin-angiotensin system inhibitors be held prior to major surgery?British Journal of Anaesthesia 2024 May
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app