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Nicorandil-induced severe oral ulceration: a newly recognized drug reaction.

R H Shotts, C Scully, C M Avery, S R Porter
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 1999 June
Nicorandil, a potassium-channel activator used for the long-term treatment of ischemic heart disease, has been recently implicated as having a drug side effect of recurrent aphthous stomatitis. Three patients are reported with drug-induced aphthouslike ulceration secondary to nicorandil.

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