We have located links that may give you full text access.
Comparative Study
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Parameters of thyroid function in the endemic goitre of Akungba and Oke-Agbe villages of Akoko area of southwestern Nigeria.
The parameters of thyroid function were determined in Akungba and Oke-Agbe communities of Akoko area, where goiter is endemic and compared to a control population of Erinmo and Ifewara in Ijesha area, both areas being in southwestern Nigeria. The two study areas have similar physical and geological settings. However, while the main carbohydrate source of the control population are yam and/or bread-fruit, the Akoko population derives her carbohydrates mainly from cassava which could lead to increased serum thiocyanate, a goitrogen. The serum level of tetraiodothyronine (T4) was significantly (P < 0.05) higher in Ifewara (11.0) and Erinmo (11.8) compared to Akungba (7.1) and Oke-Agbe (8.8[symbol: see text]micrograms/dL). The triiodothyronine (T3) was significantly (P < 0.05) higher in Ifewara (193) than Erinmo (133) and also significantly (P < 0.05) higher in Oke-Agbe (127) compared to Akungba (107 mg/dL). Conversely, thyroid stimulating hormone (TSH) (microU/mL) level was significantly (P < 0.05) higher than values obtained from Ifewara (4.5) and Erinmo (3.3). T3/T4 ratio above 25, indicative of hypothyroidism and endemic goiter, was 14, 7, 4 and 0% from Akungba, Oke-Agbe, Ifewara and Erinmo, respectively. The results of the present study clearly explain the Akoko goiter endemia in the light of modification (s) of thyroid metablism.
Full text links
Related Resources
Trending Papers
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.Diabetologia 2024 April 17
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.Mayo Clinic Proceedings 2024 April
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app