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ENGLISH ABSTRACT
JOURNAL ARTICLE
[The validation of a portable 3-channel recording system (Oxyflow, Edentec) for the diagnosis of the sleep apnea syndrome].
Archivos de Bronconeumología 2000 January
OBJECTIVE: To evaluate the usefulness of a portable recording device (Oxyflow, EdenTec) to measure oronasal airflow, oxygen saturation and arterial pulse for diagnosing sleep apnea syndrome (SAS) using conventional polysomnography as the gold standard.
METHODS: Sixty-two subjects suspected of having SAS were studied prospectively by simultaneously recording conventional polysomnography and Oxyflow data in the sleep laboratory. Two different investigators, blinded to each other's findings, interpreted the data from each method. The apnea-hypopnea index (AHI) cut-off points used were?? 10, 15 and 30. The sensitivity, specificity, positive predictive value and negative predictive value of the Oxyflow indices for each AHI cut-off point were calculated. Both computer-generated and manually collected data from the Oxyflow device were analyzed. Manual readings were recorded by two independent investigators and interobserver agreement was calculated. The usefulness of both automatic and manual analyses for SAS diagnosis was assessed using receiver operating characteristic curves (ROC).
RESULTS: Fifty-eight (93.5%) men and 4 (6.5%) women with a mean age (+/- SD) of 53 +/- 11 years (29-73) were enrolled. An AHI > or = 10 was observed in 58% of the patients and mean AHI was 25 +/- 28 (0-125). The index of respiratory disturbance per hour of analysis with desaturation events > or = 4% (RDI4%) was the parameter with the largest area under the ROC curve (0.90 for AHI > or = 10; 0.94 for AHI > or = 15 and 0.96 for AHI > or 30). Manual reading was practical and reproducible (agreement 0.93, kappa coefficient 0.82) but its efficiency was no greater than that of automatic analysis.
CONCLUSIONS: The Oxyflow device may be a useful diagnostic tool for SAS. Its portability and simplicity makes it potentially useful for in-home studies.
METHODS: Sixty-two subjects suspected of having SAS were studied prospectively by simultaneously recording conventional polysomnography and Oxyflow data in the sleep laboratory. Two different investigators, blinded to each other's findings, interpreted the data from each method. The apnea-hypopnea index (AHI) cut-off points used were?? 10, 15 and 30. The sensitivity, specificity, positive predictive value and negative predictive value of the Oxyflow indices for each AHI cut-off point were calculated. Both computer-generated and manually collected data from the Oxyflow device were analyzed. Manual readings were recorded by two independent investigators and interobserver agreement was calculated. The usefulness of both automatic and manual analyses for SAS diagnosis was assessed using receiver operating characteristic curves (ROC).
RESULTS: Fifty-eight (93.5%) men and 4 (6.5%) women with a mean age (+/- SD) of 53 +/- 11 years (29-73) were enrolled. An AHI > or = 10 was observed in 58% of the patients and mean AHI was 25 +/- 28 (0-125). The index of respiratory disturbance per hour of analysis with desaturation events > or = 4% (RDI4%) was the parameter with the largest area under the ROC curve (0.90 for AHI > or = 10; 0.94 for AHI > or = 15 and 0.96 for AHI > or 30). Manual reading was practical and reproducible (agreement 0.93, kappa coefficient 0.82) but its efficiency was no greater than that of automatic analysis.
CONCLUSIONS: The Oxyflow device may be a useful diagnostic tool for SAS. Its portability and simplicity makes it potentially useful for in-home studies.
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