We have located links that may give you full text access.
JOURNAL ARTICLE
REVIEW
Diastolic dysfunction: pathophysiology, clinical features, and assessment with radionuclide methods.
Journal of Nuclear Cardiology 2001 January
Basic to our understanding of heart failure is the distinction between systolic and diastolic ventricular dysfunction. Diastolic dysfunction implies that the ventricle cannot accept blood at normally low pressures. The ventricular filling pattern and the relation between ventricular diastolic pressure and volume reflect a dynamic interaction between time course of relaxation, conversion of elastic forces into elastic recoil, and the passive properties of the ventricle. In the early part of diastolic filling, the pressure-volume relationship is influenced primarily by relaxation; in the latter part of diastole, passive filling properties are important. Mitral inflow patterns reflect these time-varying filling dynamics and are commonly assessed with echocardiography. Disorders of diastolic filling are observed in patients with heart failure with normal ejection fraction, myocardial ischemia, and even dilated cardiomyopathy. Patients with concentric ventricular hypertrophy, normal ejection fraction, and heart failure are the prototype of patients with diastolic dysfunction. In this article we review the physiology and pathophysiology of diastole and the main clinical disorders associated with diastolic dysfunction, and we outline in brief the application of radionuclide techniques in the assessment of diastolic dysfunction.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app