We have located links that may give you full text access.
Dark lumen MR-colonography: initial experience.
PURPOSE: The aim of this study was to assess a new strategy of MR colonography for the detection of colonic polyps/malignancy. The technique is based on a rectal enema with water in combination with the intravenous application of a paramagnetic contrast agent.
METHODS: Twelve subjects were included in this study either due to suspected colorectal tumors or for screening purposes. For MR colonography the colon was filled with approximately 3000 ml of tap water while Gadobenate dimeglumine (0.2 mmol/kg) was injected intravenously. A T1w GRE sequence was acquired before and 75 sec after the contrast administration only in prone position. Three patient underwent the "bright lumen" MRC as well. All MR examinations were performed at least five days prior to conventional colonoscopy and the results of both modalities were compared.
RESULTS: The colonic filling with water resulted in a homogeneously low signal throughout the colonic lumen in all twelve subjects. Intravenous injection of gadolinium caused avid enhancement of the colonic wall. Similarly lesions arising from the colonic wall enhanced avidly. Dark lumen MR colonography correctly identified five polyps in four patients. Bright lumen MRC showed in one patient false positive results.
CONCLUSION: The new MR colonography concept based on a dark colonic lumen and a bright, contrast enhanced colonic wall turned out to be a promising alternative to the traditional MRC based on a bright lumen concept. The new technique suggests a higher accuracy in detecting polyps, a better evaluation of other parenchymal organs as well as a reduced time needed for data acquisition and analysis.
METHODS: Twelve subjects were included in this study either due to suspected colorectal tumors or for screening purposes. For MR colonography the colon was filled with approximately 3000 ml of tap water while Gadobenate dimeglumine (0.2 mmol/kg) was injected intravenously. A T1w GRE sequence was acquired before and 75 sec after the contrast administration only in prone position. Three patient underwent the "bright lumen" MRC as well. All MR examinations were performed at least five days prior to conventional colonoscopy and the results of both modalities were compared.
RESULTS: The colonic filling with water resulted in a homogeneously low signal throughout the colonic lumen in all twelve subjects. Intravenous injection of gadolinium caused avid enhancement of the colonic wall. Similarly lesions arising from the colonic wall enhanced avidly. Dark lumen MR colonography correctly identified five polyps in four patients. Bright lumen MRC showed in one patient false positive results.
CONCLUSION: The new MR colonography concept based on a dark colonic lumen and a bright, contrast enhanced colonic wall turned out to be a promising alternative to the traditional MRC based on a bright lumen concept. The new technique suggests a higher accuracy in detecting polyps, a better evaluation of other parenchymal organs as well as a reduced time needed for data acquisition and analysis.
Full text links
Trending Papers
A Personalized Approach to the Management of Congestion in Acute Heart Failure.Heart International 2023
Potential Mechanisms of the Protective Effects of the Cardiometabolic Drugs Type-2 Sodium-Glucose Transporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart Failure.International Journal of Molecular Sciences 2024 Februrary 21
The Effect of Albumin Administration in Critically Ill Patients: A Retrospective Single-Center Analysis.Critical Care Medicine 2024 Februrary 8
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app