Transepithelial Brush Biopsy: an adjunctive diagnostic procedure.

The TBBCA is an easy-to-use, chairside technique for determining the significance of an oral lesion. It was accurate in the detection of precancerous and cancerous lesions in multicenter trials. It is well accepted by patients because there is almost no pain or discomfort, minimal bleeding, and no need for sutures. It is anticipated that the introduction of this diagnostic test will increase public and professional awareness of oral precancer and cancer by promoting early detection. The TBBCA overcomes obstacles that have impacted early oral cancer detection by eliminating guesswork about which lesion requires surgical biopsy, reducing the tendency to delay referral of patients for scalpel biopsy, and reducing patients' hesitation to comply with follow-up surgical biopsy.