Testicular tissue extraction in a young male with 47,XXY Klinefelter's syndrome: potential strategy for preservation of fertility.

OBJECTIVE: To describe a case involving the cryopreservation of testis tissue retrieved from a 15-year-old male teenager with Klinefelter's syndrome.

DESIGN: Case report.

SETTING: An academic medical center.

PATIENT(S): A 15-year-old boy with Klinefelter's syndrome.

INTERVENTION(S): Microsurgical testis sperm extraction with cryopreservation of harvested tissue.

MAIN OUTCOME MEASURE(S): Spermatozoa within testis tissue.

RESULT(S): Successful extraction and cryopreservation of three vials of sperm-containing testis tissue. No effect on subsequent testosterone levels.

CONCLUSION(S): Testis tissue extraction in the adequately virilized but azoospermic young male with 47, XXY Klinefelter's syndrome may be a strategy to preserve future biological paternity.