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COMPARATIVE STUDY
JOURNAL ARTICLE
[Interval reduction of photodynamic therapy (PDT) in age-related macular degeneration (AMD) is not advantageous. A pilot project].
PURPOSE: To find out if carrying out PDT again 6 weeks after initial PDT will improve the results at 3 months.
METHODS: A total of 22 eyes were treated according to the dose regimen proposed by the TAP study.
RESULTS: After the first PDT, the CNV remained permanently closed in 14% of the eyes. Repeating the treatment 6 weeks later did not lead to permanent closure of more CNVs or a diminished size at 3 months. Short-term re-treatment had no substantial effect on the underlying choriocapillaries. Visual acuity did not profit or suffer from early re-treatment.
CONCLUSION: Shortening of the treatment interval has no serious side-effects, but does not seem to improve the results reported in the TAP study.
METHODS: A total of 22 eyes were treated according to the dose regimen proposed by the TAP study.
RESULTS: After the first PDT, the CNV remained permanently closed in 14% of the eyes. Repeating the treatment 6 weeks later did not lead to permanent closure of more CNVs or a diminished size at 3 months. Short-term re-treatment had no substantial effect on the underlying choriocapillaries. Visual acuity did not profit or suffer from early re-treatment.
CONCLUSION: Shortening of the treatment interval has no serious side-effects, but does not seem to improve the results reported in the TAP study.
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