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Idiopathic non-syphilitic paroxysmal cold haemoglobinuria in children.

G W Bird, J Wingham, A J Martin, S G Richardson, A P Cole, R W Payne, B F Savage
Journal of Clinical Pathology 1976 March
Three examples of non-syphilitic paroxysmal cold haemoglobinuria (PCH) in children are described which occurred, within a period of 16 days, in association with a febrile illness. No definite viral aetiology or obvious epidemiological association could be established. A Donath-Landsteiner antibody of anti-P specificity was demonstrated in all three patients. The serological aspects of PCH are critically discussed.

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