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Clinical Trial
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Research Support, Non-U.S. Gov't
Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency.
Neurology 2003 August 27
It is generally believed that a diet high in carbohydrate improves exercise tolerance in patients with carnitine palmitoyltransferase II (CPT II) deficiency, but it has never been systematically investigated. The authors investigated the effect of a high- vs low-carbohydrate diet on exercise tolerance in four patients with CPT II, who cycled at a constant workload of 50% of VO2max. Exercise tolerance, assessed by exercise duration and perceived exertion, improved on the carbohydrate-rich diet.
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