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Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis.
British Journal of Ophthalmology 2003 October
AIM: To compare 2% econazole and 5% natamycin in the management of fungal keratitis.
METHODS: A randomised clinical trial was performed using 2% econazole or 5% natamycin as the two treatment arms on patients presenting with culture positive fungal keratitis to the cornea service at Aravind Eye Care System, Madurai, India.
RESULTS: 116 patients were recruited, and 112 continued in the study. There were no significant differences between the two arms at baseline or for success (defined as a healed or healing ulcer) at final visit (p = 0.79).
CONCLUSIONS: 2% Econazole appears to be as effective as 5% natamycin for the management of fungal keratitis.
METHODS: A randomised clinical trial was performed using 2% econazole or 5% natamycin as the two treatment arms on patients presenting with culture positive fungal keratitis to the cornea service at Aravind Eye Care System, Madurai, India.
RESULTS: 116 patients were recruited, and 112 continued in the study. There were no significant differences between the two arms at baseline or for success (defined as a healed or healing ulcer) at final visit (p = 0.79).
CONCLUSIONS: 2% Econazole appears to be as effective as 5% natamycin for the management of fungal keratitis.
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