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JOURNAL ARTICLE
Periodic leg movements in sleep with restless legs syndrome: effect of clonazepam treatment.
Japanese Journal of Psychiatry and Neurology 1992 September
Fifteen patients with restless legs syndrome underwent whole-night polysomnographic recordings before and during clonazepam treatment. The treatment with 0.5 to 1.5 mg clonazepam improved subjective complaints of all the 15 patients. All the patients presented periodic leg movements on the polysomnograms before the treatment. The clonazepam treatment significantly decreased the total numbers of leg movements and the numbers of leg movements per hour without affecting the mean intermovement interval.
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