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Autofluorescence as a novel approach to diagnosing macular holes.

PURPOSE: To report the capability of autofluorescence as a novel approach to diagnosing macular holes.

DESIGN: Observational case report.

METHODS: In an institutional study, autofluorescence photos and optical coherence tomography scans of two patients who had surgery for macular holes were reviewed.

RESULTS: Macular hole cases had a strong subfoveal autofluorescence signal, which disappeared after surgical closure of the macular hole.

CONCLUSIONS: Autofluorescence is a novel approach to demonstrating a macular hole. This technique can also be used to confirm postoperative outcome after macular hole repair. A lack of autofluorescence corresponds to macular hole closure.

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