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Journal Article
Review
Poststreptococcal reactive arthritis: what is it and how do we know?
Rheumatology 2004 August
OBJECTIVE: To find out whether poststreptococcal reactive arthritis (PSRA) is a discrete, homogeneous clinical syndrome.
METHOD: Literature review from case reports and case series.
RESULTS: One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three percent of streptococcal isolates were group A. The clinical presentation was heterogeneous but appeared different both from that of acute rheumatic fever (ARF) and from that of HLA B27-associated reactive arthritis. Carditis was rare.
CONCLUSIONS: The term PSRA encompasses significant heterogeneity. The link between the arthritis and the streptococcal infection is unproven.
METHOD: Literature review from case reports and case series.
RESULTS: One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three percent of streptococcal isolates were group A. The clinical presentation was heterogeneous but appeared different both from that of acute rheumatic fever (ARF) and from that of HLA B27-associated reactive arthritis. Carditis was rare.
CONCLUSIONS: The term PSRA encompasses significant heterogeneity. The link between the arthritis and the streptococcal infection is unproven.
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