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Journal Article
Lowe syndrome: proton mr spectroscopy, and diffusion mr imaging.
A 3-year-old boy with Lowe syndrome had bilateral periatrial hyperintense lesions intermixed with small cyst-like changes in the periatial regions of the deep white matter at MR imaging. Proton MR spectroscopy revealed prominent myoinositol peaks suggesting the presence of gliosis. b = 1000 s/mm2 images of diffusion MR imaging were negative for the periatrial lesions. ADC maps, however, revealed high ADC values (1.76, and 1.66 x 10(-3) mm2/s), compared to the normal brain parenchyma (0.81 x 10(-3) mm2/s). These diffusion MR imaging findings likely represented gliosis.
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