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Comparative Study
Journal Article
Comparative roles of the atrial septal aneurysm versus patent foramen ovale in systemic embolization with inferences from neonatal studies.
American Journal of Cardiology 2004 November 16
Patent foramen ovale (PFO) and atrial septal aneurysm (ASA) have a significant statistical relation to ischemic strokes in adults. We reviewed their prevalence in 106 echocardiograms of neonates. Although all normal neonates have PFO, only 4% had ASA. From fetal and neonatal echocardiograms, we conclude that ASAs are more likely to be caused by inadequate size of the PFO, but the ASA can act as a funnel, enhancing the chances of paradoxic embolization in the presence of a PFO. There is no convincing evidence that an ASA alone causes strokes in adults; the confounder is probably atrial fibrillation.
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