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Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium.
Ophthalmology 2005 July
OBJECTIVE: To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium.
DESIGN: Prospective, noncomparative, interventional case series.
PARTICIPANTS: Twelve eyes of 11 patients with recurrent pterygium. The mean number of previous surgeries for pterygium was 1.9+/-1.4 (range, 1-6).
INTERVENTION: All subjects received limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C.
MAIN OUTCOME MEASURES: Pterygium recurrence and complications.
RESULTS: The mean follow-up period was 21.6+/-5.6 months (range, 16-36 months). There was no pterygium recurrence in any of the eyes. Symblepharon reappeared in 3 eyes and diplopia recurred in 2 eyes. There were no other surgical complications and there was no graft rejection.
CONCLUSIONS: Limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C may be a safe and effective procedure for recurrent pterygium.
DESIGN: Prospective, noncomparative, interventional case series.
PARTICIPANTS: Twelve eyes of 11 patients with recurrent pterygium. The mean number of previous surgeries for pterygium was 1.9+/-1.4 (range, 1-6).
INTERVENTION: All subjects received limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C.
MAIN OUTCOME MEASURES: Pterygium recurrence and complications.
RESULTS: The mean follow-up period was 21.6+/-5.6 months (range, 16-36 months). There was no pterygium recurrence in any of the eyes. Symblepharon reappeared in 3 eyes and diplopia recurred in 2 eyes. There were no other surgical complications and there was no graft rejection.
CONCLUSIONS: Limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C may be a safe and effective procedure for recurrent pterygium.
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