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Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Male/female differences in indomethacin effects in preterm infants.

Arne Ohlsson, Robin S Roberts, Barbara Schmidt, Peter Davis, Diane Moddeman, Saroj Saigal, Alfonso Solimano, Michael Vincer, Linda Wright
Journal of Pediatrics 2005 December
To test whether indomethacin prophylaxis has sex-mediated effects on severe intraventricular hemorrhage (grade III and IV) and on long-term outcomes in extremely-low-birth-weight infants. A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex.

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