JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
RESEARCH SUPPORT, NON-U.S. GOV'T
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Oral hypertonic glucose solution in the treatment of infantile colic.

BACKGROUND: Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC.

METHODS: A total of 25 infants diagnosed as typical IC were given 1 mL of 30% glucose solution or sterile water for 4 days consecutively, in a randomized, double blind crossover trial. The effect was measured by parents' scoring.

RESULTS: Parents reported varying degrees of improvement in 16 infants (64%) given glucose solution, and in 12 infants (48%) given placebo. Comparison of treatment modalities were statistically significant (P = 0.031). There was no side-effect during treatments.

CONCLUSION: The present study revealed that 30% glucose was effective in the treatment of IC. Since oral glucose solution is natural, safe, cheap and easily achievable, it might be considered as an alternative therapy.

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