Hunter syndrome (MPS II-B): a report of bilateral vitreous floaters and maculopathy.

PURPOSE: To describe bilateral vitreous opacities and maculopathy in a child with Hunter syndrome.

METHODS: A case involving fundus examination, photography, and optical coherence tomography. Medline and Embase searches found no reference to vitreous or macular abnormalities in Hunter syndrome.

RESULTS: A two-year-old boy with Hunter syndrome was found to have asymmetric, bilateral, free-floating vitreous opacities that remained stable over six years. Amblyopia and exotropia improved with occlusion therapy and spectacle correction. Visual acuity decreased when bilateral maculopathy supervened.

CONCLUSION: Screening for vitreous abnormalities and maculopathy may be important in diagnosing, treating, and explaining visual loss in Hunter syndrome.