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Case Reports
Journal Article
Acute sensory neuronopathy as the presenting symptom of Sjögren's syndrome.
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 2006 October
Sensory neuronopathy associated with Sjögren's syndrome (SS) usually has a subacute or chronic onset. We report the case of a 37-year-old woman who presented with an unusual hyperacute form of SS ganglionopathy. She initially developed paresthesias of her fingertips and rapidly became severely ataxic. Nerve conduction studies revealed abnormal sensory but normal motor functions. Lip biopsy showed findings consistent with SS. Sural nerve biopsy showed severe axonal loss. The patient showed modest improvement with immunosuppressive therapies.
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