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CSF tau protein: a new prognostic marker for Guillain-Barré syndrome.

K Jin, A Takeda, Y Shiga, S Sato, A Ohnuma, H Nomura, H Arai, S Kusunoki, M Ikeda, Y Itoyama
Neurology 2006 October 25
We measured the CSF tau protein levels in 26 patients with Guillain-Barré syndrome. The levels of the poor outcome group (Hughes grade at 6 months was between II and VI, n = 6) were higher than those of the good outcome group (0 or I, n = 20) (p < 0.0005). The higher levels of CSF tau may reflect axonal degeneration and could predict a poor clinical outcome in Guillain-Barré syndrome.

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