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The oncogenic potential of growth hormone.

Jo K Perry, B Starling Emerald, Hichem C Mertani, Peter E Lobie
Growth Hormone & IGF Research 2006 October
A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.

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