JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
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Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.

We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.

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