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Journal Article
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Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis.
Journal of Investigative Dermatology 2007 June
Prevalent mutations in the FLG gene underlie the common skin disorder ichthyosis vulgaris and are significant risk factors for atopic dermatitis (eczema). The recent publication of a strategy to sequence this difficult gene identifies a spectrum of both prevalent and rare mutations that collectively have a significant impact on susceptibility to atopic disease.
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