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HIV infection presenting with motor axonal variant of Guillain-Barré Syndrome.
Journal of Clinical Neuromuscular Disease 2007 December
OBJECTIVES: We present a case of acute motor axonal neuropathy in a patient with previously unrecognized human immunodeficiency virus (HIV) infection.
METHODS: A 46-year-old male graduate student from Mali, Africa presented with a 3-week history of progressive weakness that began during a visit home from Utah. The symptoms stabilized by 6 weeks and gradually improved without treatment.
RESULTS: Electrodiagnostic studies revealed widespread fibrillation potentials and positive sharp waves with normal sensory amplitudes and no demyelinating features. Cerebrospinal fluid pleocytosis and elevated protein prompted a test for HIV infection, which returned positive.
CONCLUSIONS: To our knowledge, this is the first case of acute motor axonal neuropathy in HIV outside of a seroconversion reaction.
METHODS: A 46-year-old male graduate student from Mali, Africa presented with a 3-week history of progressive weakness that began during a visit home from Utah. The symptoms stabilized by 6 weeks and gradually improved without treatment.
RESULTS: Electrodiagnostic studies revealed widespread fibrillation potentials and positive sharp waves with normal sensory amplitudes and no demyelinating features. Cerebrospinal fluid pleocytosis and elevated protein prompted a test for HIV infection, which returned positive.
CONCLUSIONS: To our knowledge, this is the first case of acute motor axonal neuropathy in HIV outside of a seroconversion reaction.
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