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COMPARATIVE STUDY
JOURNAL ARTICLE
MULTICENTER STUDY
RESEARCH SUPPORT, NON-U.S. GOV'T
Pregnancy outcomes after uterine artery occlusion: prospective multicentric study.
Fertility and Sterility 2008 November
OBJECTIVE: To assess the reproductive outcomes after laparoscopic uterine artery occlusion (LUAO) and uterine artery embolization (UAE) in women with symptomatic fibroids.
DESIGN: Prospective, clinical multicentric study.
SETTING: Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.
PATIENT(S): Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.
INTERVENTION(S): Laparoscopic uterine artery occlusion and UAE.
MAIN OUTCOME MEASURE(S): Pregnancy, abortion, preterm delivery, and live-birth rates.
RESULT(S): Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).
CONCLUSION(S): Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.
DESIGN: Prospective, clinical multicentric study.
SETTING: Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.
PATIENT(S): Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.
INTERVENTION(S): Laparoscopic uterine artery occlusion and UAE.
MAIN OUTCOME MEASURE(S): Pregnancy, abortion, preterm delivery, and live-birth rates.
RESULT(S): Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).
CONCLUSION(S): Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.
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