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Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Review
Visual prognosis of optic glioma.
BACKGROUND: Optic gliomas may unpredictably stabilize or progress. Prognosis was known to be better in patients with neurofibromatosis 1 (NF1) than those with non-NF1. The confusion over management is caused, at least in part, by the uncertain disease course of the tumor.
CASE HISTORY: We report here a 13-year-old girl presented with a 1-month history of a gradual decline of vision in her left eye. She was diagnosed by clinical examination and magnetic resonance imaging as having a left optic-nerve glioma and was followed by serial magnetic resonance imaging over 3 years. She and her family did not show any stigmata of NF1. Approximately 3 years after the onset of her symptoms, visual acuity, color testing, and visual fields have markedly improved with tumor regression by magnetic resonance imaging.
CONCLUSIONS: The possibility of spontaneous regression of an optic-nerve glioma should be considered even in the planning of treatment for a non-NF1 patient with this tumor.
CASE HISTORY: We report here a 13-year-old girl presented with a 1-month history of a gradual decline of vision in her left eye. She was diagnosed by clinical examination and magnetic resonance imaging as having a left optic-nerve glioma and was followed by serial magnetic resonance imaging over 3 years. She and her family did not show any stigmata of NF1. Approximately 3 years after the onset of her symptoms, visual acuity, color testing, and visual fields have markedly improved with tumor regression by magnetic resonance imaging.
CONCLUSIONS: The possibility of spontaneous regression of an optic-nerve glioma should be considered even in the planning of treatment for a non-NF1 patient with this tumor.
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