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Hyper-reactive malarial splenomegaly in a patient with human immunodeficiency virus.
American Journal of Tropical Medicine and Hygiene 2008 Februrary
Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.
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