We have located links that may give you full text access.
Sinonasal melanoma: a clinicopathologic review of 61 cases.
Otolaryngology - Head and Neck Surgery 2008 March
OBJECTIVE: To review the Mayo Clinic experience with sinonasal melanoma.
STUDY DESIGN: Retrospective review (case series).
SUBJECTS AND METHODS: We identified 61 patients who had melanoma arising from the nasal cavity, paranasal sinuses, or both. All were treated at our institution from 1955 through 2003. Clinical and pathologic data were summarized, and survival curves were generated.
RESULTS: The most common symptoms at presentation were epistaxis and nasal congestion. The most common treatment was excision only (48%). The cancer-specific survival rate (ie, rate of death due to disease) was 48.9% and 22.1% at 3 and 5 years, respectively. Median time between diagnosis and death due to disease was 19 months.
CONCLUSION: Sinonasal melanoma is a rare but devastating disease. Wide local excision is the treatment of choice, and some patients may benefit from postoperative radiotherapy. Local recurrence and distant metastasis are common. Improved survival depends on better systemic therapies.
STUDY DESIGN: Retrospective review (case series).
SUBJECTS AND METHODS: We identified 61 patients who had melanoma arising from the nasal cavity, paranasal sinuses, or both. All were treated at our institution from 1955 through 2003. Clinical and pathologic data were summarized, and survival curves were generated.
RESULTS: The most common symptoms at presentation were epistaxis and nasal congestion. The most common treatment was excision only (48%). The cancer-specific survival rate (ie, rate of death due to disease) was 48.9% and 22.1% at 3 and 5 years, respectively. Median time between diagnosis and death due to disease was 19 months.
CONCLUSION: Sinonasal melanoma is a rare but devastating disease. Wide local excision is the treatment of choice, and some patients may benefit from postoperative radiotherapy. Local recurrence and distant metastasis are common. Improved survival depends on better systemic therapies.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices 
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app