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Anxiety and salivary cortisol levels in patients with burning mouth syndrome: case-control study.

OBJECTIVE: The objective of this study was to evaluate the anxiety and salivary cortisol levels in patients with burning mouth syndrome.

STUDY DESIGN: A case-control ed into 2 groups: BMS, with diagnosis of the syndrome, and control, without any complaint of burning mouth. Anamnesis, oral examination, sialometry, the application anxiety inventory, and 3 saliva samples for cortisol analysis were done in every patient.

RESULTS: Statistical difference for subjective xerostomia was found on the BMS group (P = .01), but salivary flow rate was normal in both groups. BMS group presented higher anxiety (P = .001) and salivary cortisol levels (P = .003) when compared with the control group.

CONCLUSION: Higher anxiety and salivary cortisol levels were positively associated with the presence of BMS.

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