Somatosensory evoked cerebral potentials (SSEP) in multiple sclerosis.

INTRODUCTION: Neurological findings are the main criteria for making the diagnosis of multiple sclerosis, including head and spine MRI, CSF findings and evoked potentials.

OBJECTIVE: Investigate and observe correlation in SSEP especially wave P22 in group of healthy examiners, as well on those suffering multiple sclerosis. Present Evoked potentials clinical application benefits in Multiple sclerosis diagnostic procedures used in Neurological Clinic, Clinical Center University of Sarajevo. EXAMINES AND METHODS: Examination is prospective and clinically applicable. Examination involved one hundred examinees in total, divided in two group where 50 examinees where confirmed with Multiple sclerosis diagnosis, and 50 others made up control group of healthy volunteers. Examination is made based on neurological findings, questionnaires for EP and MS, and SSEP done for all examinees. Statistical assessment is based upon percentage, standard deviation, Chi square test and Student t test.

RESULTS: average age of patients in control group is 35.28, and at the same time 34.90 in experimental group and do not have statistical significance. In both group females were dominant gender and there was no statistical significance of gender ration between two group. Wave P22 was statistical significantly extended in group of MS diagnosed patients compared to the group of healthy examinees.

CONCLUSION: our studies dominantly affected female gender. Studies presented statistically significant increase of SSEP abnormalities in MS diagnosed patients group compared to the group of healthy examinees, in term of extended latency of waves P22 as cortical responses. These figures shows significance of SSEP clinical use in MS diagnostically procedures, to additionally confirm definite diagnosis.