Sympathetic ophthalmia following vitrectomy for endophthalmitis after intravitreal bevacizumab.

Robert A Sisk, Janet L Davis, Sander R Dubovy, William E Smiddy

Ocular Immunology and Inflammation 2008 September

PURPOSE: To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab.

DESIGN: Retrospective case report.

METHODS: An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an intravitreal injection. The inciting blind eye was enucleated.

RESULTS: Histopathology demonstrated sympathetic ophthalmia and phacoanaphylactic endophthalmitis. Visual acuity improved from 20/200 to 20/30 in the sympathizing eye with a combination of oral prednisone and azathioprine.

CONCLUSIONS: Sympathetic ophthalmia can develop following exogenous endophthalmitis but has a good visual prognosis with appropriate treatment.

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