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CLINICAL TRIAL
COMPARATIVE STUDY
JOURNAL ARTICLE
Improvement in diabetic neuropathy 4 years after successful pancreatic and renal transplantation.
Diabetologia 1991 August
We have studied the fate of diabetic neuropathy and autonomic function in 13 patients with long standing Type 1 (insulin-dependent) diabetes mellitus following combined pancreas and kidney transplantation. Fifteen diabetic patients with a kidney graft only served as controls. After initial improvement of the neuropathy in both groups, probably caused by the elimination of uraemia, a continuous improvement during the 48 months study was seen in the euglycaemic pancreas graft recipients only. Autonomic (parasympathetic) function improved only slightly and to a similar extent in both groups.
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