CASE REPORTS
JOURNAL ARTICLE
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Propionibacterium acnes brain abscess appearing 10 years after neurosurgery.

OBJECTIVE: To describe a case of Propionibacterium acnes infection arising 10 years after neurosurgery and to review the literature regarding similar cases and their treatment.

DESIGN: Case report.

SETTING: Hospital of the University of Pennsylvania.

PATIENT: A 70-year-old man with an intracerebral abscess and 2 biopsies culture positive for P acnes 10 years after subdural hematoma evacuation. Intervention Surgical biopsy followed by 6 weeks of intravenous vancomycin.

MAIN OUTCOME MEASURES: Magnetic resonance imaging, neurologic examination, and microbiology culture results.

RESULTS: Biopsies obtained from abscesses grew only P acnes. Magnetic resonance imaging and serial neurological examinations showed marked improvement after 6 weeks of intravenous vancomycin.

CONCLUSIONS: Infection by P acnes can complicate neurosurgical procedures as late as 10 years after surgery and therefore should be considered in the evaluation of patients presenting with neurologic signs and symptoms with a history of neurosurgery.

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