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Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Case report: massive blood transfusion in a patient with immunoglobulin a deficiency undergoing cesarean delivery.
Anesthesia and Analgesia 2010 April 2
Patients with immunoglobulin (Ig)A deficiency develop autoantibodies against IgA, which render them vulnerable to severe anaphylactic reactions when transfused with conventional blood or blood products containing IgA. In this report, we describe a patient with IgA deficiency and placenta accreta undergoing emergency cesarean delivery who required massive blood transfusion. We discuss the workup and treatment options in patients with known IgA deficiency.
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