We have located links that may give you full text access.
Treating the causes of paediatric hypertension using non-invasive physiological parameters.
Medical Hypotheses 2010 November
Although hypertension is uncommon in childhood, when present, clinicians should investigate the cause and manage appropriately, which can be challenging in children with renal disease. Our knowledge of normal homeostatic mechanisms of blood pressure control, such as the renin-angiotensin system or endothelial function, and the pathophysiology of these systems in hypertensive patients, has significantly advanced in recent years. However, our therapeutic strategy in paediatric hypertension is limited in delineating the underlying physiological derangement of individual patients. New non-invasive technologies are increasingly offering quantification of haemodynamic parameters to physicians. We suggest use of these parameters (normally limited to intensive care physicians by virtue of previously invasive methods of quantification) to less acute medical areas such as outpatients. If a child is hypertensive due to an elevated cardiac index then choosing anti-hypertensive agents such as beta-blockers seems appropriate. As mean arterial pressure is the product of cardiac output and systemic vascular resistance, if the cardiac output is not raised then utilising vasodilators to reduce the systemic vascular resistance is logical. Modern therapeutic strategies targeted at a child's individual physiological derangement should offer more rapid and effective anti-hypertensive medication than current therapy based on physician preference.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app