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CASE REPORTS
JOURNAL ARTICLE
Heyde syndrome--the link between aortic stenosis and gastrointestinal bleeding.
Portuguese Journal of Cardiology : An Official Journal of the Portuguese Society of Cardiology 2010 Februrary
Aortic valve stenosis can be complicated by gastrointestinal bleeding from angiodysplasia. A deficiency of high molecular weight multimers of von Willebrand factor (vWF) (type 2A von Willebrand disease) provides the link between this association, which is known as Heyde syndrome. Aortic valve replacement corrects the vWF abnormalities with long-term resolution of gastrointestinal bleeding. The authors present a case report and a review of this association.
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