We have located links that may give you full text access.
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Cognitive function in type 1 diabetic adults with early exposure to severe hypoglycemia: a 16-year follow-up study.
Diabetes Care 2010 September
OBJECTIVE: We assessed adulthood cognition in relation to early exposure to severe hypoglycemia (SH).
RESEARCH DESIGN AND METHODS: Sixteen years subsequent to a study of cognitive function in 28 diabetic children and 28 matched control subjects, we reexamined the same subjects with a 96% participation rate. Diabetic subjects were classified as with (n = 9) or without (n = 18) early (<or=10 years of age) SH, which was defined as convulsions or loss of consciousness.
RESULTS: Overall, cognitive scores were 0.9 SDs lower in subjects with early SH compared with subjects without early SH (P = 0.003). The two diabetic groups particularly differed with respect to problem solving, verbal function, and psychomotor efficiency. Earlier age at first incident of SH was associated with poorer cognition (P for trend = 0.001).
CONCLUSIONS: The findings suggest that early exposure to SH may have lasting and clinically relevant effects on cognition.
RESEARCH DESIGN AND METHODS: Sixteen years subsequent to a study of cognitive function in 28 diabetic children and 28 matched control subjects, we reexamined the same subjects with a 96% participation rate. Diabetic subjects were classified as with (n = 9) or without (n = 18) early (<or=10 years of age) SH, which was defined as convulsions or loss of consciousness.
RESULTS: Overall, cognitive scores were 0.9 SDs lower in subjects with early SH compared with subjects without early SH (P = 0.003). The two diabetic groups particularly differed with respect to problem solving, verbal function, and psychomotor efficiency. Earlier age at first incident of SH was associated with poorer cognition (P for trend = 0.001).
CONCLUSIONS: The findings suggest that early exposure to SH may have lasting and clinically relevant effects on cognition.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices 
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app