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Research Support, Non-U.S. Gov't
Rheumatoid arthritis: Are ACPA-positive and ACPA-negative RA the same disease?
Nature Reviews. Rheumatology 2011 April
Seemingly contrasting genetic backgrounds in anti-citrullinated-protein antibody (ACPA)-positive and ACPA-negative rheumatoid arthritis (RA) support the notion that these are in fact two distinct disease subsets, with different underlying pathogenesis, that might need tailored treatment strategies.
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