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Molecular diagnosis of Aspergillus fumigatus endocarditis.

José C Palomares, Samuel Bernal, María Marín, Victoria Pérez Holgado, Carmen Castro, Willy Pinto Morales, Estrella Martin
Diagnostic Microbiology and Infectious Disease 2011 August
A 66-year-old male with ischaemic cardiomyopathy and chronic lymphocytic leukemia developed signs of severe systemic inflammatory response syndrome. Serial blood cultures were negative and a SeptiFast test detected the presence of Aspergillus fumigatus DNA. Afterwards, detection of galactomannan and 1,3-β-D-glucan showed a positive result. Autopsy revealed the presence of branched fungal structures suggestive of Aspergillus.

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