Mayer-Rokitansky-Küster-Hauser syndrome: a review of 245 consecutive cases managed by a multidisciplinary approach with vaginal dilators.

OBJECTIVE: To understand the efficacy of vaginal dilators in the management of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.

DESIGN: Retrospective sequential study.

SETTING: Hospital.

PATIENT(S): 245 women.

INTERVENTION(S): Vaginal dilators.

MAIN OUTCOME MEASURE(S): Functional vaginal length and sexual satisfaction.

RESULT(S): Of the patients who completed the program, 232 (94.9%) achieved a successful vaginal length (defined as greater than 6 cm in length and maximum width throughout the vagina and especially at the apex) and sexual function. When the program was completed by all patients, 100% of patients were successful.

CONCLUSION(S): Vaginal dilator therapy is the treatment of first choice for creation of the vagina in MRKH syndrome, and the success rates suggest that surgery is rarely, if ever, required.