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Eruptive seborrheic keratoses in a young woman with acromegaly.

The sign of Leser-Trélat, or eruptive seborrheic keratoses, is purported to be a cutaneous marker for many underlying malignancies. Elevation in levels of growth factors has been postulated to be the stimulus for the sudden eruption of multiple new seborrheic keratoses. In support of this hypothesis we present a case of eruptive seborrheic keratoses in a young woman with acromegaly and elevated levels of growth hormone.

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