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Darier's disease and schizophrenia.
East Asian Archives of Psychiatry : Official Journal of the Hong Kong College of Psychiatrists 2010 December
Darier's disease, also known as Darier-White disease or keratosis follicularis, is a rare autosomal dominant genodermatosis. Clinical experience has long suggested an association between neuropsychiatric abnormalities and Darier's disease. Although there are no formal epidemiological studies confirming this association, there have been a number of reports of patients with neuropsychiatric manifestations and Darier's disease in the literature. However, most reports have come from Caucasian populations, with limited reports of Darier's disease and its neuropsychiatric associations among Asian populations. This report describes 2 Asian patients presenting with associated schizophrenia and Darier's disease.
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