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CASE REPORTS
JOURNAL ARTICLE
Another CHILD syndrome with xanthomatous pattern.
Dermatologica 1990
We report on a patient with verruciform xanthoma lesions in an epithelial nevus and developmental anomalies since birth that may be classified as CHILD syndrome (congenital hemidysplasia with ichthyosiform erythroderma and limb defects). Histological analyses of the lesion revealed verrucous features with acanthosis, hyperkeratosis, parakeratosis and the typical infiltrate of xanthomatous cells in dermal papillae. To our knowledge only 5 cases of verruciform xanthoma on epidermal nevus have been reported to date. In our view, the present case of CHILD syndrome is the first reported in which xanthomatous transformation has been revealed in biopsies taken when the girl was a baby.
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