We have located links that may give you full text access.
Thoratec VAD system as a bridge to heart transplantation.
Journal of Heart Transplantation 1990 July
As of October 1988 the Thoratec ventricular assist device system was used in 72 heart transplant candidates at 20 medical centers in five countries. All patients were in imminent risk of dying before donor heart procurement, with a mean cardiac index of 1.6 +/- 0.5 L/min/m2 and a pulmonary capillary wedge pressure of 27 +/- 8 mm Hg, in spite of maximal medical therapy. The ventricular assist device system consists of a prosthetic ventricle (Pierce-Donachy design) with a 65 ml pumping chamber, made of Thoratec's BPS-215M polyurethane, appropriate cannulae for atrial or ventricular inflow and for arterial outflow connections, and a pneumatic drive console. The devices can be used for partial or complete support of the pulmonary and systemic circulations. Fifty-eight (81%) of the 72 patients received biventricular devices and 14 received support only on the left side of the heart. Average flow rate was 5.0 +/- 0.7 L/min on the left side and 4.3 +/- 0.7 on the right. Fifty-four patients (75%) recovered sufficiently to undergo heart transplantation after a median of 4.4 days (mean, 14.3 days; range, 8 hours to 81 days), and 45 of them have been discharged from the hospital (83% early posttransplant survival and 63% overall survival from implant to discharge). Of 14 patients supported for more than 30 days, 11 underwent heart transplantation, and nine were discharged alive. The actuarial 1- and 2-year posttransplant survival rates are 78% and 75%. We conclude that these heterotopic prosthetic devices provide an effective method of maintaining blood flow to vital organs until a donor heart can be procured.(ABSTRACT TRUNCATED AT 250 WORDS)
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app