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A botryoid odontogenic cyst with multiple recurrences.

A botryoid odontogenic cyst (BOC) which recurred 4 times over a period of 9 years is presented. Immunocytochemical comparison of cytokeratin composition of the cyst epithelium with that of the overlying oral epithelium showed distinct differences. The cyst epithelium expressed keratins typical of both simple and nonkeratinizing squamous epithelia. The keratin profile of BOC is in line with previous findings on odontogenic epithelia, thus confirming its odontogenic origin.

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